The Eysz Hyperventilation (HV) Recorder is a FDA Class 1 registered software system designed to allow healthcare professionals to digitally record HV procedures - both audio and video, submit the recording for review by an Eysz Affiliated Healthcare Professional (EAHP) - a clinician under the supervision of a board-certified neurologist - and receive an electronic report based on the review by the EAHP. The intended use environment is a healthcare setting.
Hyperventilation is an activation procedure that requires rapid breathing of 20-24 breaths per minute. This procedure is known to induce absence seizures. Hyperventilation was recognized as an effective test to provoke absences by Otfrid Foerster (1873–1941), a German neurologist and neurosurgeon, in 1924.
The American Clinical Neurophysiology Society has guidance stating that Hyperventilation should be used routinely unless medical or other justifiable reasons (e.g., a recent intracranial hemorrhage, significant cardiopulmonary disease, sickle cell disease or trait, or patient inability or unwillingness to cooperate)
contraindicate it.
The effectiveness of this diagnostic tool even provides fodder for Holowach and O’Leary’s suggestion that a diagnosis of absence epilepsy “should be seriously questioned [if one] does not have an attack on hyperventilation.” (Holowach et al., 1962). The International League Against Epilepsy has guidance that in resource- limited regions, CAE can be diagnosed in children without EEG, if clincian has witnessed typical absence seizure with HV.
Spike Wave Discharges are triggered by voluntary hyperventilation in over 90% of patients with absence epilepsy (Glauser, 2013; Wirrell, 1997; Caplan, 2008, 2015; Panayiotopoulos, 1999), a phenomenon initially documented in the early 20th century (Watemberg, 2015; Giannakodimos et al., 1995).
Hyperventilation can be used to assist pediatricians in evaluating kids with staring spells and/or inattention and to optimize referral process to neurologists.
Once a child has been diagnosed with childhood absence epilepsy, hyperventilation can be used as a management tool to confirm presence of absence seizures, especially in low-resourced settings where EEG is not readily available.
Hyperventilation can be used to confirm presence of absence seizures prior to starting a neuropsych examination.
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